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Everything to Know About Autoimmune Diseases

Updated
5/28/25
Written by:

David Mayer

When an autoimmune disorder occurs, your body’s defense system turns against you, leading to a range of confusing and persistent symptoms. Autoimmune diseases affect millions of people, causing the immune system to mistakenly attack healthy tissues. At Osprey PolyClinic, we’re here to help you understand these conditions and find answers. Whether you’re experiencing unexplained fatigue or joint pain, consulting a primary care physician could be your first step toward clarity and relief.

What Are Autoimmune Diseases?

What Are Autoimmune Diseases?

Autoimmune diseases occur when the immune system, which typically protects the body from infections and harmful invaders like bacteria and viruses, malfunctions. Instead of targeting only threats, the immune system's abnormal response begins attacking healthy cells and tissues. This misdirected immune response can lead to inflammation, pain, and damage over time.

Some autoimmune diseases focus on specific organs. For example, Type 1 diabetes damages the pancreas, impairing insulin production. Others, like lupus, are systemic, affecting multiple parts of the body, such as the skin, joints, and kidneys. Over 80 known autoimmune diseases exist, and many autoimmune diseases present unique challenges. Understanding how the immune system shifts from protector to aggressor is key to managing these conditions effectively.

Types of Autoimmune Diseases

Most Common Autoimmune Diseases

Autoimmune diseases vary widely in their targets and symptoms. Here are some of the most common types:

  • Rheumatoid arthritis (RA): The immune system attacks joint linings, causing inflammation, stiffness, and pain.
  • Lupus (Systemic lupus erythematosus): A systemic condition that can affect the skin, joints, kidneys, and more, often with a characteristic butterfly rash.
  • Type 1 diabetes: Destroys insulin-producing cells in the pancreas, requiring lifelong management.
  • Multiple sclerosis (MS): Damages the protective coating around nerve fibers, disrupting movement and coordination.
  • Psoriasis & psoriatic arthritis: Triggers scaly skin patches and, in some cases, joint inflammation.
  • Celiac disease: A reaction to gluten that harms the small intestine, leading to digestive issues.
  • Hashimoto’s thyroiditis: Attacks the thyroid, slowing hormone production and causing fatigue or weight gain.
  • Graves’ disease: Overstimulates the thyroid, leading to symptoms like rapid heartbeat and weight loss.
  • Inflammatory bowel disease (IBD): Includes Crohn’s disease and ulcerative colitis, affecting the digestive tract.

These conditions highlight the diversity of autoimmune diseases, each requiring tailored care.

What Causes Autoimmune Diseases?

The exact causes of autoimmune diseases remain unclear, but several factors, including blood cells,  may contribute:

  • Genetics: A family history of autoimmune diseases increases your risk, suggesting a hereditary component.
  • Environmental triggers: Infections, exposure to toxins, or even prolonged stress might activate an autoimmune response in susceptible individuals.
  • Hormonal factors: Autoimmune diseases are more common in women, possibly due to hormonal changes during puberty, pregnancy, or menopause.
  • Gut health: Emerging research points to imbalances in the gut microbiome as a potential trigger for immune dysfunction.

While these factors don’t guarantee an autoimmune disease, they can combine to tip the scales. For instance, a viral infection in someone with a genetic predisposition might spark symptoms. Understanding these risks can guide prevention and early intervention efforts.

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Get the Answers You Need From a Specialist

If you’re experiencing unexplained fatigue, joint pain, or skin issues, it may be time to see a specialist. Book a consultation at Osprey PolyClinic today!

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Common Symptoms of Autoimmune Diseases

Autoimmune diseases often share overlapping symptoms, making them tricky to identify. Look out for chronic fatigue, joint pain or stiffness, skin rashes, and digestive problems like bloating or diarrhea. Brain fog, muscle weakness, and recurring flare-ups — where symptoms worsen then subside — are also common. These signs can mimic other conditions, so tracking them is crucial for diagnosis.

How Are Autoimmune Diseases Diagnosed?

Diagnosing an autoimmune disease can be a lengthy process due to symptom overlap. It typically starts with a detailed medical history and symptom review. Blood tests, like the Antinuclear Antibody (ANA) autoimmune disease test or blood transfusions , detect immune activity, while Rheumatoid Factor (RF) or C-Reactive Protein (CRP) measure inflammation. Thyroid function tests or organ-specific imaging, like MRIs or biopsies, may also be used. Because symptoms fluctuate, testing for autoimmune disease often requires patience and persistence.

Treatment for Autoimmune Diseases

Managing autoimmune diseases, which often target healthy body tissue,  involves a mix of medical treatments and lifestyle changes tailored to each condition.

Medications

  • Immunosuppressants: Reduce immune system overactivity (e.g., methotrexate).
  • Anti-inflammatory drugs: Ease pain and swelling (e.g., NSAIDs or corticosteroids).
  • Biologic therapies: Target specific immune pathways (e.g., for RA or MS).

Lifestyle Adjustments

  • Anti-inflammatory diet: Focus on whole foods, omega-3s, and avoiding processed sugars.
  • Exercise: Low-impact activities like yoga or swimming improve mobility.
  • Stress management: Techniques like meditation or therapy help reduce flare-ups.

Alternative Therapies

Options like acupuncture, physical therapy herbal supplements, or probiotics for gut health may complement traditional care, though evidence varies.

Importance of Ongoing Care

Regular visits to an autoimmune disorder doctor, such as a rheumatologist or endocrinologist, ensure symptoms stay controlled. Combining these approaches can improve quality of life significantly.

Start Managing Your Autoimmune Health at Osprey PolyClinic

Living with an autoimmune disease doesn’t have to mean constant struggle. At Osprey PolyClinic in Sarasota and SW Florida, our specialists are ready to help you take charge of your health. Schedule a consultation and start your journey to better well-being.

David Mayer
David Mayer
President and COO
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FAQs

How long can you live with an autoimmune disease?

Life expectancy varies by condition and management, especially in cases where the immune system destroys healthy body tissue . With proper treatment, many people live full lives, though severe cases like lupus may pose complications if untreated.

Can I reverse autoimmune disease?

There’s no cure, but some patients reduce symptoms that may trigger autoimmune disease rough diet, stress management, and medication. Reversal isn’t guaranteed, but remission is possible.

What is the best lifestyle for autoimmune disease?

A balanced diet, regular exercise, adequate sleep, and stress reduction form the foundation. Work with a specialist to personalize your plan.

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